Allen C Gao Selected Research

Androgen Antagonists (Antiandrogens)

1/2020	Cross-Resistance Among Next-Generation Antiandrogen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer.
10/2019	AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer.
10/2018	Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer.
1/2017	Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer.
9/2015	Antiandrogens Inhibit ABCB1 Efflux and ATPase Activity and Reverse Docetaxel Resistance in Advanced Prostate Cancer.
6/2014	Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer.
8/2013	NF-κB2/p52 induces resistance to enzalutamide in prostate cancer: role of androgen receptor and its variants.
3/2009	Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2.
7/2006	Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA).

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Allen C Gao Research Topics

Disease

104	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 07/2002
56	Neoplasms (Cancer) 01/2022 - 07/2002
7	Neoplasm Metastasis (Metastasis) 12/2018 - 01/2003
4	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2005
4	Carcinogenesis 05/2012 - 04/2005
4	Lung Neoplasms (Lung Cancer) 04/2012 - 04/2005
3	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2022 - 03/2008
3	Melanoma (Melanoma, Malignant) 12/2019 - 04/2004
2	Adenocarcinoma 01/2022 - 12/2019
2	Hypoxia (Hypoxemia) 01/2019 - 05/2006
2	Hyperplasia 02/2011 - 05/2006
1	Arthritis (Polyarthritis) 01/2021
1	Circulating Neoplastic Cells 01/2019

Drug/Important Bio-Agent (IBA)

51	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 07/2002
48	AndrogensIBA 01/2021 - 07/2002
22	enzalutamideIBA 01/2021 - 08/2013
14	Interleukin-6 (Interleukin 6)IBA 09/2015 - 01/2003
13	abirateroneIBA 01/2021 - 04/2015
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2004
12	Docetaxel (Taxotere)FDA Link 10/2021 - 03/2013
11	SeleniumIBA 04/2012 - 01/2004
10	Hormones (Hormone)IBA 01/2021 - 09/2003
10	Prostate-Specific Antigen (Semenogelase)IBA 12/2018 - 07/2002
9	Androgen Antagonists (Antiandrogens)IBA 01/2020 - 07/2006
6	cabazitaxel FDA Link 10/2021 - 10/2016
6	Niclosamide FDA Link 01/2021 - 06/2014
6	Pharmaceutical PreparationsIBA 01/2021 - 03/2010
5	Small Interfering RNA (siRNA)IBA 11/2020 - 09/2004
5	SurvivinIBA 08/2012 - 07/2007
4	taxaneIBA 10/2021 - 10/2018
4	LigandsIBA 10/2020 - 04/2005
4	CytokinesIBA 09/2012 - 09/2004
4	methylselenic acidIBA 04/2012 - 04/2006
4	NF-kappa B p52 SubunitIBA 04/2010 - 07/2007
4	Interleukin-4 (Interleukin 4)IBA 02/2009 - 09/2003
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 07/2019
3	Indomethacin (Indometacin)FDA LinkGeneric 01/2021 - 04/2015
3	Taxoids (Taxanes)IBA 02/2020 - 10/2018
3	Testosterone (Sustanon)FDA Link 10/2019 - 08/2009
3	MicroRNAs (MicroRNA)IBA 01/2019 - 01/2012
3	bicalutamide (Casodex)FDA LinkGeneric 01/2017 - 03/2009
3	ChromatinIBA 04/2013 - 05/2006
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2012 - 01/2003
3	NF-kappa B (NF-kB)IBA 01/2008 - 07/2005
3	Messenger RNA (mRNA)IBA 04/2005 - 04/2004
2	olaparibIBA 01/2022 - 07/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2020
2	darolutamideIBA 01/2021 - 01/2020
2	apalutamideIBA 01/2021 - 01/2020
2	EnzymesIBA 01/2021 - 08/2009
2	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2019 - 11/2018
2	UbiquitinIBA 10/2019 - 11/2018
2	SteroidsIBA 10/2019 - 04/2015
2	RNA (Ribonucleic Acid)IBA 01/2019 - 05/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2012 - 07/2007
2	sanguinarineIBA 01/2012 - 03/2010
2	AlkaloidsIBA 01/2012 - 03/2010
2	Antineoplastic Agents (Antineoplastics)IBA 11/2011 - 03/2010
2	andrographolideIBA 02/2011 - 08/2010
2	Estrogen ReceptorsIBA 03/2008 - 04/2005
2	Oncogene Proteins (Oncogene Protein)IBA 07/2007 - 09/2004
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2007 - 09/2004
2	MetriboloneIBA 05/2006 - 09/2003
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022
1	LGK974IBA 01/2021
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021
1	Monoamine Oxidase (MAO)IBA 01/2021
1	Prednisone (Sone)FDA LinkGeneric 01/2021
1	aminophenylacetylleucine (APAL)IBA 01/2021
1	AminesIBA 01/2021
1	Steryl-Sulfatase (Steroid Sulfatase)IBA 11/2020
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2020
1	Abiraterone AcetateIBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	Cell Surface ReceptorsIBA 12/2019
1	Chemokine ReceptorsIBA 12/2019
1	Phenobarbital (Luminal)FDA Link 12/2019
1	Phosphotransferases (Kinase)IBA 12/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2019
1	trametinibIBA 12/2019
1	Leuprolide (Lupron)FDA LinkGeneric 10/2019
1	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 10/2019
1	BuffersIBA 10/2019
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 10/2019
1	B7-H1 AntigenIBA 01/2019
1	Alkaline PhosphataseIBA 12/2018
1	Circulating Tumor DNAIBA 12/2017
1	RNA Splicing FactorsIBA 12/2017
1	QuercetinIBA 12/2017
1	LipidsIBA 10/2017
1	Growth Hormone (Somatotropin)IBA 01/2017
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2016
1	Adenosine Triphosphatases (ATPase)IBA 09/2015
1	Co-Repressor ProteinsIBA 06/2015

Therapy/Procedure

57	Castration 01/2021 - 02/2009
43	Therapeutics 01/2021 - 07/2002
4	Drug Therapy (Chemotherapy) 10/2021 - 03/2010
2	Chemoprevention 11/2008 - 04/2005
1	Precision Medicine 01/2022
1	Prostatectomy (Retropubic Prostatectomy) 12/2019